Symposium on Nonlinear Dynamics in Biology

May 8 - May 11, 2000
Niels Bohr Institute, Auditorium U, Blegdamsvej 17
University of Copenhagen

Funded by The Danish Research Academy through the Graduate School of Biophysics and the Graduate School of Nonlinear Science

Organizing committee: Sune Danø, Erik Mosekilde and Preben Graae Sørensen








Monday (May 8)

Cell Synchronization in Beta-Cells

9:00 - 9:45        Erik Mosekilde: "Synchronization of coupled pancreatic cells"
                              (Physics Department, Technical University of Denmark, Denmark)

9:45 - 10:50      Svend Göpel and Juris Galvanovskis: "Electrical activity of pancreatic
                              beta-cells in intact islets: Experimental and theoretical aspects"
                              (Institute of Physiology, University of Lund, Sweden)

10:50 - 11:20    coffee

11:20 - 12:30    Ole Skyggebjerg: "Acquisition and analysis of calcium waves in pancreatic
                               islets using fluorescence videomicroscopy"
                               (Novo Nordisk A/S, Denmark)

                              Mette Vesterager Petersen: "A mathematical model of wave
                              propagation in coupled beta-cells"
                              (Dept. of Mathematical Modelling, Technical University of Denmark, Denmark)

12:30 - 13:30  lunch

Cell Synchronization in Yeast Cells

13:30 - 14:15  Preben Graae Sørensen: "Glycolytic oscillations in open flow systems"
                            (Dept. of Chemistry & CATS, University of Copenhagen, Denmark)

14:15 - 15:00  Martin Bier: "How yeast cells synchronize their glycolytic oscillations"
                            (Dept. of Plastic & Reconstructive Surgery, University of Chicago, USA)

15:00 - 15:30  coffee

15:30 - 16:00  Silvia De Monte: "Locked states of a population of nonlinear oscillators"
                            (Universita' degli Studi di Milano, Italy)

16:00 - 16:30  Francesco d'Ovidio: "Modelling perturbations in a population
                             of coupled oscillators"
                             (CATS, Technical University of Denmark and
                            University of Copenhagen, Denmark)

Bioinformatics

16:30 - 17:00  Bai-lin Hao: "Fractals from genomes: Exact solutions of
                             a biology-inspired problem"
                             (Institute of Theoretical Physics, Academia Cinica, China)
 

Tuesday (May 9)

Bacterial Pattern Formation

9:00 - 9:30     James A. Shapiro: Introduction
                           (Dept. of Biochemistry and Molecular Biology,
                          University of Chicago, USA)

9:30 - 10:15   Sune Danø: "Physical and biological basis of pattern formation
                           in Proteus mirabilis"
                           (Dept. of Chemistry & CATS, University of Copenhagen, Denmark)

10:15 - 11:00  Michael Givskov: "Cell-cell comunication and organized
                             behavior of bacteria"
                             (Dept. of Microbiology, Technical University of Denmark)

11:00 - 11:30  coffee
 

11:30 12:15    Mitsugu Matsushita "Periodic colony formation of bacteria"
                          (Dept. of Physics, Chuo University, Japan)
 

12:15-12:45    Discussion on bacterial pattern formation.
                            Why does it happen? What does it teach us?

12:45 - 13:45  lunch

Reaction-Diffusion Systems

13:45 - 14:30  Thomas Mair: "Traveling waves of glycolytic activity"
                            (Dept. of Biophysics, Otto-von-Guericke-Universität, Germany)

14:30 - 15:15  Mads Ipsen: "Pacemakers in oscillatory reaction-diffusion systems"
                            (Dept. of Physical Chemistry, Fritz-Haber-Institut der MPG, Germany)

15:15 - 15:45  coffee

15:45 - 16:45  Mads Kærn: "Physical principles of segmentation during growth"
                            (Dept. of Chemistry, University of Toronto, Canada)

16:45 - 17:30  Sergey Kuznetsov:  "Instabilities and pattern formation in
                             the reaction-diffusion flow model"
                             (Inst. of Radio Engineering, Saratov, Russia)
 

Wednesday (May 10)
 

Fungal Patterns

 9:30 - 9:45    Elena Bystrova: "Modelling of pattern formation in mycelial fungi colonies"
                           (Dept. of Biophysics, Saint-Petersburg State University, Russia)

Bioreactors

 9:45 - 10:30  Frede Lei: "Modelling and control of multiple steady-states in
                           a continuous baker's yeast cultivation"
                           (Dept. of Chemical Engineering, Technical University of Denmark, Denmark)

10:30 - 11:00  coffee

Modelling Biological Systems

11:00 - 11:45  Hans Braun: "Cooperative effects between nonlinear dynamics and noise:
                             sensory receptors, hypothalamic neurons and psychiatric disorders"
                             (Institute of Physiology, University of Marburg, Germany)

11:45 - 12:30  Mitsugu Matsushita "Formation of colony patterns by bacterial cell population"
                            (Dept. of Physics, Chuo University, Japan)

12:30 - 13:30  lunch

13:30 - 14:15  Finn Hynne: "A full-scale model of glycolysis"
                            (Dept. of Chemistry & CATS, University of Copenhagen, Denmark)

14:15 - 14:45  coffee

14:45 - 15:30   Anton Antonov:  "A pattern language for large scale air pollution models"
                             (UNI-C, Denmark)

15:30 - 16:15   Zhanybai Zhusubaliyev: "Bifurcations and chaotic oscillations in an
                             automatic control relay system with hysteresis"
                             (Dept. of Computer Science, Kursk State Technical University, Russia)
 

Thursday (May 11)

Combining Experiments and Models

 9:00 - 9:45   Tom Fenchel: "Motile behaviour of microbes: Individual
                             responses and effect at the population level."
                          (Marine Biological Laboratory, University of Copenhagen)

 9:45 - 10:30  Stanley Brown: The genetic switch in lambda phage: experiments
                           (Institute of Molecular Biology,
                           University of Copenhagen, Denmark)

10:30 - 11:00  coffee

11:00 - 11:45 Kim Sneppen: The genetic switch in lambda phage: a model
                            (NORDITA, University of Copenhagen, Denmark)

11:45 - 12:45  Dennis Bray: "Bacterial chemotaxis: models and experiments"
                            (Dept. of Zoology, University of Cambridge, UK)

12:45                 lunch