Biological cybernetics, i. e. self-organization and autonomous control in biochemical feedback systems.

Study of oscillations and waves, simulations of biochemical networks, bifurcations in nonlinear biochemical reaction-diffusion systems, spontaneous biological pattern formation and morphogenesis, Turing patterns.

The main activities are in the context of physical-chemistry studies of Ilya Prigogine's school (the Brussels group): The results have been presented in invited talks, among these a number of NATO workshops organized by the Brussels group and others, and in Brussels under EU's ERASMUS program.

A. Hunding, F. Kepes, D Lancet, A Minsky, V. Norris, D. Raine, K. Sriram, R. Root-Bernstein: 'Compositional complementarity and prebiotic ecology in the origin of life',

* BioEssays * 28 pp 399-412 (2006)
Article (PDF 357K)

A. Hunding:
'Microtubule Dynamics may Embody a Stationary Bipolarity
Forming Mechanism Related to the Prokaryotic Division
Site Mechanism (Pole-to-Pole Oscillations)',

* Journal of Biological Physics * 30 pp 325-344 (2004)
Article (PDF 137K)

A. Hunding, G. Ebersbach and K. Gerdes: `A mechanism for ParB-dependent waves of ParA, a protein related to DNA segregation during cell division in prokaryotes',

* Journal of Molecular Biology * 329/1 pp 35 - 43 (2003)
Article (PDF 291K)

A. Hunding and M. Ipsen: `Simulation of waves in calcium models with 3D spherical geometry',

* Mathematical Biosciences * 182/1 pp 45 - 66, (2003),
Article (PDF 404K)

M. Kaern, M. Menzinger, R. Satnoianu and A. Hunding: `Chemical waves in open flows of reactive media: Their relevance to axial segmentation in biology',

* Faraday discuss. * 120, pp 295-312, (2001)
Article (PDF 484K)

M. Kaern, M. Menzinger and A. Hunding: `Segmentation and Somitogenesis Derived from Phase Dynamics in Growing Oscillatory media',

* J. theoret. Biol.* 207, pp 473-493, (2000)
Article (PDF 642K)

A. Hunding and R. Engelhardt: `Self-Organization and Evolution in a Simulated Cross Catalyzed Network'

* Origs. Life Evol. Biosphere * 30 (5): pp 439-457,
(October 2000).
Article (PDF 147K)

M. Kaern and A. Hunding: `Dynamics of the cell cycle engine: Cdk2-kinase and the transition into mitosis',

A. Hunding and M. Kaern: `The Effect of Slow Allosteric Transitions in a Simple Biochemical Oscillator Model',

A. Hunding and R. Engelhardt: `Early Biological Morphogenesis and Nonlinear Dynamics',

A. Hunding: `Nonlinear Dynamics in Biochemical Control Systems',

A. Hunding: `Modeling Spatial Pattern Formation in

A. Hunding, S.A. Kauffman and B.C. Goodwin: `

A. Hunding and M. Brons, `Bifurcation in a Spherical Reaction-Diffusion System with Imposed Gradient',

A. Hunding: `Spontaneous Biological Pattern Formation in the Three-Dimensional Sphere: Prepatterns in Mitosis and Cytokinesis',

A. Hunding: `Possible Prepatterns Governing Mitosis: The Mechanism of Spindle-Free Chromosome Movement in